How to Profit from the EU Referendum?

I imagine that the big players will be backing their judgment and building substantial positions in preparation for the forthcoming referendum. If they're right, they'll make some serious coin. In the lead up to the referendum, my guess is that the markets will become increasingly volatile and, immediately after it when the result is known, there could be some large swings in the major FX pairs and equity indices. So, whatever your view - in or out - if you wanted to take a punt and back your judgement - how would you go about it?

I'm undecided about which way I'll vote, but I suspect that Dave C' and the 'stay in' crowd will win the day. Based on that, what instrument should I buy (or sell) to get the biggest bang for my buck - and why?

Discuss!

How to Profit from the EU Referendum?